New Cancer Treatment May Ease Nerves

This article was originally published in the fall 2018 issue of Imagine magazine. Courtesy of Pride of IU website For patients who have just received a cancer diagnosis, the immediate need is clear: battling the life-threatening dangers of the cancer itself. Yet often overshadowed in this fight are the serious side effects of many treatments, which can take a devastating toll on patients’ quality of life....

NIH Awards Grant for Research on APX3330 as Treatment for Cancer Cachexia

INDIANAPOLIS, Ind. – Researchers will continue to explore the impact of Apexian’s target molecule, APX3330, on cancer cachexia with additional grant funding from the National Institutes of Health (NIH) National Cancer Institute (NCI). Cancer cachexia is weight loss with chronic inflammation and defective metabolism, which causes roughly one-third of all cancer deaths. It is particularly prevalent in pancreatic ductal adenocarcinoma (PDAC), which has a dismal...

Kelley Presents at National Institutes of Health

Dr. Mark Kelley, Chief Scientific Officer of Apexian Pharmaceuticals, presented a special seminar at the National Institutes of Health on October 3 on his research on APX3330's effect on the Ref-1/APE signaling node in cancer and chemotherapy-induced neuropathy. In addressing the National Institute of Environmental Health Sciences, Dr. Kelley discussed the progress of this promising therapy from benchtop to the current phase 1 clinical trial.